Body Could Fight Cancer

Canadian scientists find way to trigger immune response

By HAYLEY MICK The Globe and MailTue. Apr 28 - 4:46 AM

TORONTO — Canadian scientists have discovered how to trigger an improved immune response to cancer that — if researchers’ hopes come true — could lead to treatments that use a patient’s own cells to hunt down and destroy tumours.

The findings, published online Sunday in the journal Nature Medicine, demonstrate the exciting potential of immunotherapy in cancer treatment, says principal investigator Pamela Ohashi, a researcher at

Toronto’s Princess Margaret Hospital.

"If we learn to do this right, (cancer) will be just like having symptoms for a cold or flu. It will be allowing the body to attack the tumour, and in that sense, you won’t have to do chemotherapy and all those treatments."

Ohashi and colleagues from Toronto, Germany and the U. S. combined a vaccine with a naturally occurring substance in the body called interleukin-7 (IL-7), a protein that helps white blood cells ward off disease.

The combination dramatically extended the lives of mice with pancreatic cancer. Those that received treatment for two weeks died in 120 days, compared with the 80-day lifespans of those that did not.

"It essentially bought the mouse what would be the equivalent of years (of time) in humans," said Tak Mak, a co-author of the study who, with Ohashi, heads the Campbell Family Institute for Breast Cancer Research.

While the vaccine component triggered the immune response, Researchers discovered that IL-7 helped white blood cells work more effectively in killing the tumour. It also broke down several barriers that would normally stop the white blood cells from attacking the body’s own tissue.
"It allowed (the white blood cells) to get to the tumour site and stay there and do their job," Ohashi said. Since IL-7 operates throughout the body, the treatment could be applied to others cancers, she added.

The promise of using the body’s own defences to fight cancer has intrigued scientists for years.

Not only is the human immune system better equipped to specifically target diseases inside the body, but immunotherapy treatments would also spare cancer patients from the side effects of more traditional therapies that can be invasive, such as surgery, or toxic, such as chemotherapy.

A legion of vaccines are being studied and tested around the world to treat brain, lung, skin, kidney and other cancers — with some success. The HPV vaccine, for example, is now being administered to young girls to prevent cervical cancer.

But most cancers are not caused by viruses, Ohashi said. So researchers are now looking for ways to trigger the immune system to attack cancers after they appear in the body.

One of the reasons IL-7 is generating so much excitement, Mak added, is because it has already been found to be non-toxic in humans. Another naturally occurring immune component called IL-2 can be effective in fighting kidney cancer, he said. But when administered to mice, it’s so toxic that it often kills off the mouse before it eradicates the tumour.

"If we learn to do this right, (cancer) will be like having symptoms for a cold or flu."
PAMELA OHASHI cancer researcher.

Primary OfficePrincess Margaret Hospital

10th Floor Rm. 1030

620 University AveToronto,

OntarioCanada M5G 2C1

pohashi@uhnres.utoronto.ca

More on Craig Lane...

Good morning..my 1st update in over 2 weeks........

After 27 days, Craig is OFF the life-support. (the ventilator is still on stand-by) but a little positive news.Now he is getting some oxegen thru his trach. They changed his trach yesterday to a smaller one and the next step is to get it capped. After that he should be able to talk. He is off sedation but still on pain-killers so he still has not opened his eyes and no response when we talk to him. Hopefully that will all change soon. He's not out of the woods by no means but its looking up. he now has been moved to isolation in the ICU b/c his white blood counts are really low. Its been 4 days since they drained fluid from his belly so that's good. They drained 16 liters in 2 days earlier this week.

I want to sincerly thank all of you who been so supportive to us at this very stressful time.

May God bless each and everyone of you,

Take care,

Jean, Austin and all the Lane family....

PS..Craig has said many times since he has been sick that if you don't have your health, family & friends, you have nothing....and he's right

Drug Coverage Options On Caring Vocies Tonight

Please join us Tuesday on http://www.caringvoices.ca/ Drug Coverage Options
This event is hosted by the General Cancer community.

Date/Time: April 21, 2009 at 1:00 PM ESTDuration: 1hrs

Drug coverage is a very real concern that many cancer patients and caregivers have to face. Join Pharmacist Sophie Kim and Social Worker Valerie Heller from Princess Margaret Hospital to learn about drug coverage options available to you.

Moderators: Sophie Kim, Valerie Heller

Craig Battling Strongly Future Brighter

Craig's brother Jason sent this report on Thursday, april 9, 2009 (Ed. note).

Hi,

Craig went into the OR this morning at 11am (they had a few cancellation so they were able to schedule him in there this morning). Within an hour they had the temporary tracheotomy in place, and everything went fine. He is resting well, and everything else (blood pressure, heart rate) are stable. They cut back on some of his blood pressure meds (phenylephrine) so that is looking good. As long as his blood work continues to look good, they will continue with 2 chemo treatments next week.

The plan is now to continue to monitor everything, and ween him off the sedation and gradually ween him off the ventalator too. They will monitor this daily, and it sounds like they can tweak this once they see how he is reacting to it. Gradually they can ween him off the sedation and ventalator and get him to a point where he is breathing on his own. It also sounds like he may have the trach in when he leaves the ICU as well (for a short period of time anyway, then he can get that taken out).

They did drain 1 L from his belly today, and they continue to give him the albumen protein too. It had been 2 days since they drained any fluid. His belly is still swollen, but they don't want to be draining too much. At this point now, we're wondering if the chemo or the other medication will start taking affect and eventually help with the absorption of the nourishmnet so the fluid doesn't come back. I would think that'll be a longer process over the weeks/months ahead.

Jason

More on Craig Lane's Condition Wednesday Update

Wednesday, April 1, 2009 update:

Craig is still sedated, on the ventalator, resting well, with blood pressure, heart rate at normal levels. His blood pressure did drop a bit, so they did a CT scan as a precautionary measure, and the results were all good. No problems.

They put a clamp on the tube that was draining the fluid from his belly, and the tube draining fluid from his lung will likely be removed tomorrow. They did a bit of physio to get him moving his limbs.

They continue to monitor to see if he's absorbing the nourishment and the extra protein they are giving him.

Jason

Craig Lane's Photo From Webshots

Left, Craig's mother Jean Lane.
The link below connects to a photo of Peoms Multiple Myeloma patient Craig Lane from Newfoundland, who the entire multiple myeloma community sends best wishes for a speedy recovery. Craig if there is anything further we can do to help you, please let us know. Thank you Jason and Jean Lane, Lady Newfoundland.

Frank Boyd (Ed.)

Craig pictures from art photos on webshots

Updates On Craig MM POEMS Patient

This from Jason,today Sunday, March 29, 2009; I have requested a photo of Craig, Frank Boyd Ed.

Jason here. Just got back from a long day at the hospital. I stayed over last night. it was a pretty quiet night, but by 6am Craig was feeling some anxiety due to the pain. His hip was sore with the way he was lying on the bed. So he was agitated and his oxygen level was low. The nurses took him down to the ICU around 2pm and he's been there since. His blood pressure is low, so they are monitoring that too. His heart rate was high, but he is resting now and that has come down. His oxygen levels are back to 100% and he just got some pain medication. He is feeling discomfort, but they will monitor his condition tonight. They will also do a chest CT scan to make sure there's no blood clotting or infection where the drainage tube is. He's getting lots of attention in the ICU so that's good. He has lots and lots of visitors, but only family can go into the ICU. Hopefully the levels will be stable over night and he can go back up to the 4th floor room (if not tomorrow then on Tuesday). We'll keep you posted.Jason


This from Craig's Mother Jean on Wednesday, March 25, 2009

Hi Frank..Thanks again for your help. I have heard from many MM and POEMS patients. Craig's main Dr came in today and said she was talking to Dr Angela and she gave her some suggestions but Dr Angela didn't think they should use thalidomide. They are coming in tomorrow to explain it all to us.
Today Craig had his 3rd amount of belly fluid removed (21 liters in all 3) but they have left the tube in and have it clamped and will let some more off in a couple days. He has been in hospital 82 days lying flat on his back...he's starting to go stir-crazy..Its been hard for us as well. His brother is coming tomorrow from BC for the second time.We are missing home but will stay on as long as it is neccesary.

Many Thanks for all who have helped,

Jean Lane

We are not put on this earth to see through one another, but to see one another through.

POEMS PATIENT'S MOTHER THANKS MYELOMA COMMUNITY

Alan Suher, CT, USA

In 1998 I woke up with all of my toes numb. This was the beginning of what would be six months of doctors, tests, more doctors and more tests. I feel very lucky that after only a half year a new Neurologist, I had an appointment with, came to a possible conclusion that I had POEMS Syndrome. He said if he is right the illness is beyond him, but he had about four doctors, in various states, that he felt were familiar with POEMS. Thanks for your help Alan, Frank

Myeloma patients from across North America banded together to help a Newwfoundland POEMS patient they have never met. The patient's mother thanks everyone as she writes:

"Hello Frank..I just wanted to let you know I spoke to the Dr. this morning and this afternoon she came in to say she had called Dr. Angela and spoke with her secretary and left a message..Its 11PM and we just got home from the hospital since 10 this morning..

Thanks for all your help and the help of others who have emailed me,

Jean"

We are all pulling for Mrs. Lane's son and I will give you updates on his progress. Meanwhile I want to thank the myeloma team for a team effort. RUFF! RUFF! RUFF!

Multiple Myeloma Patient, Richard Brown, a Top Curler

Canadian wheelchair curling championship begins Monday, March 23, 2009 in Lower Sackville.

Nova Scotia’s best wheelchair curlers will take on a strong field at the Canadian Wheelchair Curling Championship beginning Monday at the Lakeshore Curling Club in Lower Sackville.

One of these champion curlers, Richard Brown, underwent a stem cell transplant last February 2008 at the same time as I did. Richard and his lovely wife Sharron are delighted that Richard is going to get to play, and so am I.

Brown, 62, was an able-bodied curler at the club level, curling out of Mayflower for 17 years, before a spinal tumour led to surgery in late 2007.

His condition, multiple myeloma, is treatable, but incurable, and he now has titanium rods in his spine. However, extensive rehabilitation at the Nova Scotia Rehab Centre has allowed him to get around with the help of a walker and, more recently, canes.

This is his first year playing the wheelchair game.

"It’s a lot different because there’s no sweeping," said Brown. "You have to be pretty accurate with your throwing, a lot more accurate than you are in the able-bodied game."

Good luck Richard and Sharron and let us know how you are doing. We are all so proud of you.

Frank

POEMS Re-visited Advise from Jeffrey Hoffen and Alan Suher

Just receive is some very crucial information regarding POEMS from Alan Suher. Please vidsit his website at: http://poemssyndrome.info/. I have forwarded his email to Mrs. Lane and her son.

For those who need this valuable information here is what Alan wrote:

Hi,

My name is Alan Suher and I diagnosed with POEMS in 1998. During these 10 years I have learned a lot and I am glad to pass some information on to you. Being in a hospital that has never treated a POEMS patient is not a good situation. In all honesty they don't know what to do because they haven't run this course before. They will do a lot of "trail and error stuff" and that is not the answer.

My recombination's:

Have the doctor in charge of the case contact Dr Angela Dispenzieri the Mayo Clinic in Rochester, MN (USA). The phone number is 507-284-2479. Dr. D. is one of the few doctors in the world that understand POEMS and how to treat it.

Sign up on ACOR.ORG and communicate with other POEMS patients. What could be more helpful then being able to talk to others that have already gone through this route?
Finally, go to the website POEMSSYNDROME.INFO This is a website I recently developed for POEMS patients.

These are my suggestions. If I can me of further assistance, please write me at suher@cox.net
Good luck,

Alan Suher in CT (USA)

Thank you Alan and Jeffrey Hoffen

Here is what Jeffrey wrote:

Hi Mr. Boyd

I saw a quick note about someone with POEMS who might need assistance. A website and community of POEMS patients does exist. The web site was generally put together by Alan Suher (email below).

You can contact him, or me, for further information. Dr. Dispenzieri at Mayo is the leading expert on POEMS. Also, if patient can not get to Mayo I would recommend an Academic tertiary care hospital-one that is affiliated with a medical school. This is a complex disease.

JH

AN APPEAL FOR HELP WITH MM/POEMS

I received this email from Mrs. Lane and her aooeal for help. I am asking anyone out there who has pertinent information to help. Here's Mrs. Lane's eamil:

I saw your email on the Myeloma website for Atlantic Canada. My son, age 46 was diagnosed in November with CIDP. After 2 months not getting any better, he was admitted to hospital on January 6th and has been there every since. He was diagnosed with MM and several days later told he also has a rare syndrome POEMS..Its now been 2 1/2 monthas and he has had several treatments,Dex ( steriods) 13 radiation treatments and is now on chemo for 4 treatments, 14 days apart. The hospital is now in the process of getting thalitomide from the US.He has severe polyneuropathy and is bedridden 24/7..This is the 1st case of POEMS for the hospital so this is all new to them as well as us.Any information would begreatly appreciated,Thank You,Jean Lane.

I offered this help, but I am also asking that you out there who read this post to also help:

Dear Mrs. Lane,

Pray is a powerful thing but in order to help yourselves you and your son need to know what it is you are dealing with. There are many resources at your disposal, among which is the Mayo Clinic online. There you may find out what you are dealing with. Information is your greatest strength; another are the people with POEMS and they are perhaps your greatest resource.

With the first part, reliable information is paramount. I suggest you go online to (click the link below; you may have to ctrl click it):

www.mayoclinic.org/poems/symptoms.html

Don’t let it frighten you; above all you need faith and belief in your son’s recovery or medical control by your doctors of what he has. Another source of information is NINDS.

National Institute of Neurological Disorders and Stroke (NINDS) find CIDP Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

www.ninds.nih.gov/disorders/cidp/cidp.html

Click on this link. Again do not let this frighten you, you must control you emotions.

Finally, you must seek out those who have your son’s condition and the IMF is the best location I can think of and its list server is the location to find help. Here is the link to the IMF

http://myeloma.org/main.jsp

When there go to find support; there’s a link at the top of the page. Get on the List Server where other MMers communicate. Ask for help, information on your son’s condition and those with it will respond and overwhelm you with information and therapies. Remember, you are not ALONE; there’s HELP. Don’t give up, PRAY and get into ACTION. I have copied this to my friend Susan and she can help you also.

I sincerely hope this helps,

Frank Boyd
Susan Trites

(902) 463-0070

IF ANY OF YOU CAN HELP PLEASE EMAIL ME AT:
frankboyd@airfire.ca

ONJ Osteonecrosis of the jaw

Osteonecrosis of the jaw in patients with multiple myeloma treated with zoledronic acid.

Cetiner S, Sucak GT, Kahraman SA, Akı SZ, Kocakahyaoglu B, Gultekin SE, Cetiner M, Haznedar R.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gazi University, Ankara, Turkey.

Intravenous bisphosphonates-the potent inhibitors of osteoclast-mediated bone resorption are among the most commonly prescribed drugs in the management of multiple myeloma (MM). Zoledronic acid (ZA) is a new generation potent intravenous bisphosphonate that has been approved for the treatment and prevention of bone lesions, and/or hypercalcemia associated with MM. Osteonecrosis of the jaw (ONJ) is an emerging serious side effect of the new generation bisphosphonates with a growing number of reports related to this pathological entity. ONJ usually appears following oral surgical and dental procedures but sometimes occur spontaneously. These cases are mostly seen and treated by dentists and oral surgeons. The aim of this study was to discuss the frequency, characteristics, risk factors, management and histopathological features of ZA induced ONJ based on the literature and illustrated with five own cases. Thirty-two patients with MM who received ZA for a median period of 26.5 +/- 18.7 months (min: 5 months, max: 76 months) were evaluated. ONJ was detected in five patients and mean drug duration time was 34 months. The frequency was 15% and the patients were usually symptomatic. There was no significant difference in terms of the duration of ZA in patients with and without ONJ. Management of these established cases were performed with medical treatment, minor debridement, sequestrectomy, and combining bone resection with autologous platelet rich plasma. Our data indicate that ZA therapy has a major role in the development of ONJ a fact that should be considered by physicians treating MM patients.

Elderly Multiple Myeloma Patients

New generation pharmacotherapy in elderly multiple myeloma patients.

Ataergin SA, Kindwall-Keller T, Berger NA, Lazarus HM.

Gulhane (GATA) Faculty of Medicine Department of Medical Oncology and Bone Marrow Transplantation Unit, 06018, Etlik, Ankara, Turkey.

BACKGROUND: Observational databases have demonstrated that the overall prognosis of multiple myeloma patients has markedly improved over the past decade, yet the greatest strides have been attained in younger rather than older patients. OBJECTIVE: To review recent clinical trials that include new generation agents (thalidomide, lenalidomide and bortezomib) and autologous stem cell transplantation in older multiple myeloma patients. RESULTS: Conventional regimens such as melphalan plus prednisone can be improved with the addition of thalidomide or bortezomib: more patients attain complete and near-complete remission, and progression-free survival rates are nearly doubled. In addition, autologous hematopoietic stem cell transplantation studies show that this treatment approach can be used successfully in selected older myeloma patients in whom the toxicity profile of autotransplant and resulting overall survival may be similar to that obtained in the younger patient group. CONCLUSIONS: In the advanced-age population, implementation of new therapies results in significant benefits in older as well as younger patients.

Emerging Therapies for Multiple Myeloma

Emerging therapies for multiple myeloma.

Podar K, Tai YT, Hideshima T, Vallet S, Richardson PG, Anderson KC.
Dana-Farber Cancer Institute, Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Boston, MA 02115, USA. klaus_podar@dfci.harvard.edu

Multiple myeloma (MM) is a clonal plasma cell malignancy clinically characterized by osteolytic lesions, immunodeficiency, and renal disease. There are an estimated 750,000 people diagnosed with MM worldwide, with a median overall survival of 3 - 5 years. Besides chromosomal aberrations, translocations, and mutations in essential growth and tumor-suppressor genes, accumulating data strongly highlight the pathophysiologic role of the bone marrow (BM) microenvironment in MM pathogenesis. Based on this knowledge, several novel agents have been identified, and treatment options in MM have fundamentally changed during the last decade. Thalidomide, bortezomib, and lenalidomide have been incorporated into conventional cytotoxic and transplantation regimens, first in relapsed and refractory and now also in newly diagnosed MM. Despite these significant advances, there remains an urgent need for more efficacious and tolerable drugs. Indeed, a plethora of preclinical agents awaits translation from the bench to the bedside. This article reviews the scientific rationale of new therapy regimens and newly identified therapeutic agents - small molecules as well as therapeutic antibodies - that hold promise to further improve outcome in MM.

PMID: 19249983 [PubMed - in process

MULTIPLE MYELOMA FACT SHEET

What is multiple myeloma?

Multiple myeloma is an incurable yet treatable cancer of the blood in which plasma cells are overproduced in the bone marrow. Plasma cells are a type of white blood cell found in bone marrow that produces the antibodies to help the body fight infections.[i] Multiple myeloma occurs when abnormal cells develop in the bone marrow and divide uncontrollably, eventually crowding out healthy blood cells. Over time these cells can spread to the solid part of the bone, causing fractures and pain.

Fast Facts

Multiple myeloma is the second most prevalent blood cancer after non-Hodgkin's lymphoma and accounts for 1.3 per cent of all new cancer cases in Canada and 1.9 per cent of all cancer deaths.[ii]

According to the most recent Canadian Cancer Society statistics, of the approximately 6,000 Canadians living with the disease, about 1,350 will die this year and 2,100 new patients will be diagnosed across Canada.

Once considered a disease of the elderly, the average age at diagnosis of people with multiple myeloma is the early 60s, with many patients much younger.
Multiple myeloma affects slightly more men than women.

Causes and risk factors

Despite the tremendous amount of work that has gone into the search into the cause of myeloma, to date no cause of this disease has been identified. However, a possible link between exposure to chemicals, pollutants, radiation, or other environmental risk factors and a greater risk of developing myeloma has been suggested.[iii] In most cases, individuals who develop multiple myeloma have no clear risk factors.

Symptoms and diagnosis

There are often no symptoms in the early stages of myeloma. In some cases, myeloma may be discovered by accident during routine blood testing. When present, symptoms may be vague and similar to those of other conditions.

The growth of malignant plasma cells in the bone marrow crowd out healthy blood cells and impact the body in a number of ways, including:

• Producing fewer red blood cells, which can result in anemia and fatigue;
• Suppressing healthy white blood cell production, which can lead to recurrent infections;
• Attacking and weakening of bones, which may lead to osteoporosis and result in considerable pain and potential fractures;
• Affecting normal kidney and nerve functions.

Because myeloma is a very complex disease, patients may experience all or none of the above symptoms. The diagnosis of multiple myeloma is often made by way of a routine blood test for other conditions. The existence of anemia and a high serum protein may suggest further testing.[iv]

[i] Canadian Cancer Society. What is multiple myeloma? Available online at:

http://www.cancer.ca/Ontario/About%20cancer/Types%20of%20cancer/What%20is%20multiple%20myeloma.aspx?sc_lang=en Accessed February 17, 2009.

[ii] Myeloma Canada: Cause and Incidence; http://www.myelomacanada.ca/en/incidence_prevalence.htm?t=1 Accessed February 17, 2009.

[iii]Myeloma Canada. Stronger together. (pamphlet). Fall 2008.

[iv] Myeloma Canada. Diagnosis. Available online at: http://www.myelomacanada.ca/en/diagnosis.htm Accessed on February 17, 2009.

ANGUS REID POLL RESULTS: CANADIANS ON CANCER

A SURVEY OF PRECEPTIONS AND ATTITUDES OF CANADIANS TOWARD CANCER AND ACCESS TO MEDICATIONS

SUMMARY OF FINDINGS

KEY FINDINGS
A recent national survey shows that Canadians are divided on how confident they are about having access to the necessary medications, if they were diagnosed with cancer. In fact, 43% of respondents indicated they were not confident that they would have access to the cancer medications they would need.

· Although they are divided in their confidence about having access to the necessary cancer medications, Canadians are optimistic in that they tend to see cancer as something you can live with (64%), as opposed to something you will necessarily die from.

· Greater access to cancer treatments ranked second only to reduced wait times among a list of four potential priorities for government health care spending.

· After being told about the current public insurance coverage for cancer treatments in Canada, the vast majority of Canadians (86%) stated that provincial government programs should pay for all cancer medications approved by Health Canada for those eligible - even if it meant a re-allocation of health care dollars. 84% of respondents felt that all of the provincial governments should have a common list of cancer drugs that they cover instead of having different coverage lists in each province.

· Very few (15%) correctly identify multiple myeloma as a blood cancer. A third (33%) mistakenly identified it as a type of skin cancer and another third (36%) admitted to not knowing what it is.


SURVEY METHODOLOGY

The findings reflect results of a nationwide online survey of adult Canadians conducted by Angus Reid Strategies on behalf of Myeloma Canada. The study was conducted among a randomly selected, representative sample of 1,002 adult Canadians. Below is the breakdown by region:
· British Columbia: n=140
· Alberta: n=123
· Manitoba/Saskatchewan: n=63
· Ontario: n=356
· Quebec: n=224
· Atlantic: n=96

The data were collected between November 14 and 16, 2008. The margin of error for results based on the total sample of 1,002 is +/- 3.1%, 19 times out of 20. Results have been statistically weighted according to Statistics Canada’s most current education, age, gender and region Census data to ensure a representative sample of the entire adult population of Canada.

- 30 -

For more information, please contact:
Rosalind O’Connell
Hill & Knowlton Canada
(416) 413-4773
rosalind.oconnell@hillandknowlton.ca

Myeloma Canada's Post-ASH Myeloma Web Conference

THE POST-ASH MYELOMA WEBINAR IS HAPPENING A WEEK FROM TODAY: FEBRUARY 18

IF YOU HAVE NOT YET REGISTERED, CLICK ON THE LINK BELOW TO COMPLETE THE ONLINE REGISTRATION FORMREGISTRATION IS FREE

DON’T MISS OUT ON THIS UNIQUE OPPORTUNITY TO LEARN ABOUT THE LATEST RESEARCH AND ADVANCES IN THE TREATMENT OF MYELOMA

http://www2.eventsvc.com/myeloma/021809

In its continuing efforts to provide valuable information and updates to the Canadian myeloma community, Myeloma Canada is presenting a national web conference (webinar) highlighting the advances in myeloma research presented at the recent American Society of Hematology (ASH) meeting held in San Francisco.

The annual ASH meeting is the most important international gathering of clinicians and scientists where the latest research findings in the management of multiple myeloma and other blood disorders are presented and discussed.

Dr Christine Chen of the Princess Margaret Hospital in Toronto and member of Myeloma Canada’s Scientific Advisory Board, will lead the presentation. A 30-minute question and answer session will follow.

Date
Wednesday, February 18, 2009

Time
British Columbia & Yukon: 4:00 pm (Pacific)
Alberta: 5:00 pm (Mountain)
Saskatchewan & Manitoba: 6:00 pm
(Central)Ontario & Quebec: 7:00 pm
(Eastern)Maritimes & Labrador: 8:00 pm
(Atlantic)Newfoundland: 8:30 pm

Requirements
Telephone
Computer
Internet connection

Registration
Registration is free. You are required to register in order to receive the toll-free call-in number and participate in the conference.Simply click on the following link to complete the online registration form.

http://www2.eventsvc.com/myeloma/021809

You are invited to pass this information along to anyone who would benefit from the information that will be presented in the webinar.

------ End of Forwarded Message

Caring Voices Website

Caring Voices is an online community for cancer survivors. You can use this site to access current resources, learn about upcoming survivorship events, take part in chats and discussions and meet other survivors just like you. Below is this week's schedule of events. To use this site you need to register as a user and it is well worth your while to register. Ed.

Please join us this week on http://www.caringvoices.ca/

Managing Your Fatigue with Renewed Strength
This event is hosted by the General Cancer community.
Date/Time: January 06, 2009 at 8:00 PM EST Duration: 1hrs

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Join Dee Miller, personal trainer and founder of Renewed Strength to discuss how strength and mobility training can help you manage some of the side effects of your cancer treatment. Renewed Strength is a non profit company dedicated to providing strength and mobility training to individuals that have recently gone through cancer treatments such as radiation, chemotherapy and surgery. Radiation Therapy: Your Questions, Before, During and After Treatment, Moderator: Dee Miller.

This event is hosted by the Breast Cancer community.
Date/Time: January 07, 2009 at 12:00 PM EST Duration: 1hrs

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Do you have questions relating to radiation therapy treatment for breast cancer? Or perhaps you would like to share your radiation therapy experience with other breast cancer survivors who are about to begin or have started their treatments? Please join this open chat about Radiation Therapy treatments for Breast Cancer with Shannon Pearson, Clinical Specialist Radiation Therapist.
Moderators: Shannon Pearson
And Looking Ahead . . . . . .Talking Sticks: Meet other Survivors Online

This event is hosted by the Breast Cancer community.
Date/Time: January 13, 2009 at 8:00 PM EST Duration: 1hrs

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Join this open chat for breast cancer survivors who have something they want to talk about or who just want to chat with others who understand their past, present or future experiences.
Moderators: Karen Portelli Spirituality and Cancer

This event is hosted by the General Cancer community.
Date/Time: January 14, 2009 at 12:00 PM EST Duration: 1hrs

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"Spirituality is that part of each individual that longs for meaning, integrity, beauty, dignity, love, acceptance and hope." For many, a diagnosis of cancer brings these themes to the surface in a way they may not have been experienced before. Some have experienced attention to spirituality and it's many expressions to be a foundational resource to cope with life's challenges. You're welcome to join in a time of reflection and discussion regarding that which may have been a support or a challenge to you, personally, in the area of spirituality, and to learn from the experiences of others.

Moderators: Sharon Konyen
A special event in collaboration with Wellspring!Putting Yourself First

This event is hosted by the General Cancer community.
Date/Time: January 14, 2009 at 7:30 PM EST Duration: 1.5hrs.

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With a cancer diagnosis, the need to put yourself first can be a change and a challenge. Join us to discuss various self-care strategies and how to cope with demands and expectations (including saying 'no') in order to create a space for healing. Moderator: Paula Servin, MSW, RSW.Presented on behalf of Wellspring Cancer Support Centres, http://www.wellspring.ca/

Moderators: Paula Servin
Talking Sticks: Open Chat for Survivors

This event is hosted by the Breast Cancer community.
Date/Time: January 16, 2009 at 12:00 PM EST Duration: 1hrs

Join this open chat for breast cancer survivors who have something they want to talk about or who just want to chat with others who understand their past, present or future experiences.
Moderator: Fiorella Lubertacci